Basic Informations

C.V

Curriculum vitae
Personal information:
Name: Eman Magdy Ahmed Muhamed
Address: W6 Building, Sama Al- Kahera, Maadi ring road, Cairo.
Cell phone: 01001077882
E- Mail address: emysanfora82@ yahoo.com
Birth date: 10- 12- 1982
Birth place: Cairo
Nationality: Egyptian
Marital status: Married
Current position: Assistant lecturer in Oral medicine, Diagnosis, Radiology and Periodontology department, Al Nahda Univeristy, Bani Suif.
Education:
? Bachelor Degree, Cairo University, May 2006 with a very good degree.
? Master Degree, Cairo University, Oral medicine and Periodontology department, 2014.
Career experience and skills:
? 2006-2010: worked as general practitioner in Ministry of Health Hospitals.
? 2011-2015: working as member of the teaching team in Periodontology, Oral medicine, Diagnosis and Radiology under direct supervision of my teachers at Al Nahda University:
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Prof. Dr. Kareman Al Soudany (Prof. of periodontology, Tanta University)
Ass. Prof. Dr. Osama Gouda (Ass. Prof. of periodontology, Suiz Canal University)
Ass. Prof. Dr. Hala Helmi Hazaa (Ass. Prof. of periodontology, Al Azhar University)
Dr. Lma Al Marsafy (Lecturer of Oral medicine Al Nahda University)
? Honoured to be chosen by my professors and my students as well to be the best demonstrator (2013- 2014).
? Worked as member in quality assurance and accreditation team in Al Nahda University.
? One of the scientific committee at Nahada University first international conference.
? Speaker and organiser of NUB’s first international conference.
? Registered for PhD in Oral medicine and special care dentistry Cairo University 2015-2016 and till now. A PhD research entitled: “Platelet lysate to manage oral mucositis resulted from methotrexate treatment in rheumatoid arthritis”
? Trainee in oral Medicine and Periodontology department and Oral Surgery department, faculty of Oral and Dental medicine, Cairo University. I worked as an Assistant and Operator Surgeon under direct supervision of:
Prof. Dr. Soheir Abd Al Ali Gaafar (Professor of Oral medicine and diagnosis, Cairo University)
Prof. Dr. Manal Muhamed Hosny (Professor of Periodontology, Cairo University)
Prof. Dr. Shahira Al Esheiry (Professor of Periodontology, Cairo University)
Prof. Dr. Samar Al Kholy (Professor of Periodontology, Cairo University)
Ass. Prof. Dr.: Weam Rshwan (Ass. prof. of Oral medicine and Diagnosis, Cairo University)
Ass. Prof. Dr. Tarek Al Ghareeb (Ass. Prof. of Oral surgery)
Ass. Prof. Dr. Hala Helmy Hazzaa (Ass. Prof. of Periodontology, Al-Azhar University)
? Management of periodontal surgeries as:
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-Root coverage with gingival grafts (C.T and epithelial grafts)
-Gingvectomy, gingvoplasty.
- Esthetical Crown lengthening, functional crown lengthening.
- Modified widmen flaps.
- Frenectomy, frenotomy and frenal relocation.
- Sulcus deepening and lip relocation as a treatment of gummy smile.
-Management of Aggressive periodontitis patients
- Attended and participated in distraction osteogensis surgery under direct supervision of Dr. Tarek Al Gareeb, department of Oral surgery, Cairo University.
? Management of medical emergencies.
? Management of patients with systemic diseases and oral mucosal diseases.
? 1st aid skills.
? Fluent English language.
? Computer skills.
? Teaching skills.
Courses:
? Courses in Quality Assurance and Accreditation of Education:
o Institutional self-evaluation cycle of higher education institutions at National Authority for Quality Assurance and Accreditation of Education (Oct 2012).
o Learning outcomes and curriculum maps at National Authority for Quality Assurance and Accreditation of Education (Nov 2012).
o External Audit Institutions of Higher Education at National Authority for Quality Assurance and Accreditation of Education (Apr 2013).
? Courses in infection control at Ministry of health.
? Courses in educational skills at Al Nahda University.
? Courses on Research planning, research publication, scientific writing and systematic review development
Research work:
? MSc. Thesis in oral medicine titled: “Evaluation of Monocyte Chemotactic Protein-1 in saliva as an early sign of metabolic disorders in patients with chronic kidney disease” under supervision of my Professors:
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Prof. Dr. Soheir Mohamed Gaafar, Professor of Oral Medicine, Oral Diagnosis and Periodontology, Faculty of Oral and Dental Medicine, Cairo University
Prof. Dr. Laila Mohamed Rashed, Professor of Medical Biochemistry, Faculty of Medicine, Cairo University
Ass. Prof. Dr. Weaam Rashwan, Associate professor of Oral Medicine, Oral Diagnosis and Periodontology, Faculty of Oral and Dental Medicine, Cairo University.

Master Title

Evaluation of monocyte chemotactic protein (MCP-1) in saliva as an early sign of metabolic disorders in patients with chronic kidney disease

Master Abstract

Summary The oral health is a mirror of the systemic health of the human body, systemic diseases may be affected by the oral health or give oral manifestations and sometimes oral manifestations may be the early signs of the systemic disease. Chronic kidney disease is one of the systemic diseases accompanied by worsen oral and periodontal condition. A bidirectional relation will result in further deterioration of the renal disease due to the neglected oral hygiene. (Fisher et al. 2011). There are many mechanisms by which chronic kidney disease can affect the oral cavity; uremia, hyperparathyroid hormone, anemia, oxidative stress and and the dramatic rise in inflammatory mediators such as IL-1, IL-6,TNF-a, CRP and MCP-1(Thorman et al. 2010). The oral mucosa, salivary glands, teeth and even periodontal tissues all are affected by the disease (Sunil et al. 2012). Complications of chronic kidney disease could be prevented if the condition was early detected and controlled; metabolic complications and cardiovascular complication are the most serious complications of chronic kidney disease (Levey et al. 2011); both can be early detected and controlled. One successful approach to control the complications is to monitor the inflammatory mediators such as MCP-1(Thorman et al. 2010) a key chemokine; its increasing level translates the decline in renal function (Murea et al. 2012) and predates the onset of its serious complications (Nishi et al. 2011). Summary 141 Saliva is a noninvasive successful diagnostic method that can be used to diagnose and monitor many systemic diseases. The salivary composition and volume can predict many diseases and reflect the systemic condition. Almost all disease markers detected in serum or urine are also detectable in saliva (Sebastien et al. 2010). Salivary changes in chronic kidney disease are due to increased concentration of urea, hyposalivation, hyperphosphatemia, increased inflammatory mediators and oxidative stress (Vahedi et al. 2012). MCP-1 in saliva not only predicts the complications of chronic kidney disease but also jeopardizes the periodontal health (Gupta et al. 2013). The aim of the present study was to evaluate the levels of pro-inflammatory cytokines (MCP-1) a biomarker in secreted stimulated saliva of patients with CKD as an early sign of metabolic disorder for those patients and its effect on their oral condition. The current study was conducted on 50 individuals, selected from the outpatients’ clinic in the oral medicine and periodontology department, Faculty of oral and dental medicine, the chronic kidney disease clinic outpatients, and the nephrology department inpatients, Faculty of medicine, Cairo University Hospital. They were divided into 4 groups as follow: Group 1: consists of fifteen patients with a GFR 59-30 ml/min/1.73 m2 “Stage3”. Group 2: consists of fifteen Patients with a GFR 29-15 ml/min/1.73 m2 “Stage 4”. Group 3: diseased control group, consists of ten individuals with chronic moderate to severe periodontitis, these patients were selected to be medically free. Group 4: control group, consists of ten individuals, these patients were selected to be medically free. Summary 142 Patients were subjected to full history taking, full clinical examination to oral and dental tissues including examination of the oral mucosa, plaque index, gingival index, and clinical attachment level for evaluation of the periodontal condition and stimulated salivary sample collection for evaluation of MCP-1 and evaluation of the salivary flow rate. Quantitative data were presented as mean and standard deviation (SD) values. Data were explored for normality using Kolmogorov-Smirnov and Shapiro-Wilk tests. Age, salivary flow rate, MCP-1 levels and CAL data showed parametric distribution while DMFT index and its components, GI and PI data showed non-parametric distribution. In the present study GFR values were used to describe the decline in renal function in the two CKD stages. MCP-1 values were compared to GFR in different CKD stages in salivary samples; the results showed that salivary MCP-1 values are inversely proportional to the GFR values. Salivary MCP-1 values were statistically correlated to all other parameters in this study; age, salivary flow, DMFT, GI, PI and CAL. The results have shown that a direct proportional relation was found between MCP-1 and age, M score (number of missing teeth), DMFT, GI, PI, CAL. An inverse proportional relation was found between MCP-1 and D score (number of decayed teeth), F score (number of filled teeth) and salivary flow rate. The results of this study were as follow: The salivary MCP-1 values were higher in stage 4 CKD or the late stage (464± 84.7 pg/ ml), followed by stage 3 CKD or the early stage (273.5± 42.1 pg/ ml), the chronic periodontitis group (147.5± 20.9 pg/ ml) and the healthy control group (114.3± 8.2 pg/ml). Summary

PHD Title

Evaluation of topical human platelet lysate versus topical clobetasol in management of methotrexate-induced oral ulceration in rheumatoid arthritis patients: Randomized-controlled clinical trial

PHD Abstract

Summary Ulcers are common symptoms observed in the oral cavity and some ulcerations are induced by drug medications. When ulcers show typical clinical findings diagnosis may be easy, but the management could not be at the same ease. Many kinds of drugs have been reported to cause oral ulcerations. Among them, non-steroidal anti-inflammatory drugs, drugs for the treatment of chronic disorders such as, diabetes, angina pectoris, rheumatoid arthritis, and osteoporosis. Methotrexate (MTX) is a well-established chemotherapeutic agent used for treatment of acute lymphocytic leukemia, lymphomas, choriocarcinoma, and some solid tumours. It is increasingly used in low-dose regimes for a variety of non-neoplastic conditions and its uses and adverse effects are of increasing significance to dentists. Rheumatoid arthritis (RA) is the most common rheumatic disease, and low-dose (5-20 mg per week) methotrexate (MTX) is used extensively as a line of treatment of RA. Low dose MTX has been associated with many toxic effects oral ulceration and mucositis are common adverse effects. Through the published data, the management of MTX induced oral ulcer was achieved by cessation or temporarily omission of the MTX dose until re-epithelialization. Up to July 2018, the electronic data bases searched didn’t have any randomised clinical trial addressing management of MTX induced oral ulcer in RA patients. The objective of the present study was to compare the clinical efficacy of Human platelet lysate and topical corticosteroid in managing MTX induced oral ulcers in RA patients. Summary 90 A total sample size of thirty patients were enrolled. Patients were randomly allocated into two groups, group A (the intervention or HPL) and group B (the control or clobetasol). Pain was assessed as a primary outcome on daily bases for 7 days, one week and two weeks after treatment using numerical pain scale. Oral mucositis assessment to evaluate oral ulcer clinical improvement as secondary outcome on one week and two weeks after treatment using WHO mucositis scale. The results of the present study has shown a statistically significant pain reduction both in daily bases and weekly assessment in the intervention group compared to the control group. The oral ulcer clinical improvement was statistically significant in the intervention group compared to the control group.